Dados do Trabalho

Título

Prognostic Factors in Elderly Septic Patients: Insights from a Private ICU

Objetivo

To assess the clinical profile of elderly septic patients admitted to a private ICU in João Pessoa and identify factors associated with their outcomes.

Métodos

This cohort study analyzed elderly patients (>65 years) diagnosed with sepsis (Sepsis 3) admitted to a private ICU in João Pessoa, Brazil, in 2023.

Resultados

A total of 218 elderly patients were included, with 71.6% presenting with septic shock. The median age was 80 years, with SOFA scores of 3, MFI scores of 0.18, Charlson Comorbidity Index (CCI) of 1, and SAPS3 scores of 49. Females made up 58.7% of the cohort, and 78.9% were admitted from the Emergency Department. Dementia was prevalent in 33% of cases, with 23.4% classified as frail. The median ICU stay was 3 days, and mortality was 9.6%. Non-survivors had significantly higher SAPS3 (65 vs. 48, p<0.001), CCI (5 vs. 1, p<0.001), and MFI scores (0.36 vs. 0.18, p<0.001). Multivariate analysis revealed SAPS3 as the strongest predictor of mortality (OR 1.07, p=0.024). SAPS3 demonstrated excellent predictive accuracy for mortality (AUROC 0.831), while SOFA, CCI, and MFI scores did not show significant predictive value.

Conclusão

In elderly septic patients, SAPS3, CCI, and MFI scores were associated with increased mortality, with SAPS3 showing the highest predictive accuracy. Each 1-point increase in SAPS3 corresponded to a 7% higher risk of death, underscoring its value in clinical prognostication.